QUANTITATIVE CONTENT OF MINERAL ELEMENTS IN HERBAL COLLECTION WITH HEPATOPROTECTIVE ACTIVITY
Keywords:
herbal collection, hepatoprotector, elemental composition, ICP-MS method, micro- and macroelements, environmental safety.Abstract
The ICP-MS method was used to determine the elemental composition of the herbal collection with hepatoprotective activity, including raw materials of domestic medicinal plants: red clover herb, milk thistle fruits, sandy immortelle flowers and corn silks with stigmas. The analysis revealed the presence of 61 mineral elements. The content of such essential elements as potassium, calcium, phosphorus, magnesium, sodium, etc., which have a positive effect on the vital functions of the body, was also noted. It was ascertained that the analyzed medicinal herbal collection is environmentally safe, since the content of toxic elements in it does not exceed permissible values.
References
Dementieva T.M., Kompantseva E.V., Sannikova E.G., Frolova O.O. Macro- and
microelements of the bark and shoots of some willow species growing in the North Caucasus
// Far Eastern Medical Journal. - 2017. - No. 3. - P. 56-59.
Khalilova Sh.R., Urmanova F.F. Hepatoprotective effect of dry extract of red clover //
Current achievements of pharmaceutical technology and biotechnology: collection of
scientific works, issue 3. - Kh.: University University, 2017. pp. 308-310.
Ramazanov A.Sh., Balaeva Sh.A., Shakhbanov K.Sh. Chemical composition of fruits and oil
of milk thistle growing in the Republic of Dagestan // Chemistry of plant raw materials.
No. 2. P. 113-118. doi:10.14258/jcprm.2019024441.
Smirnov S.O., Fazullina O.F. Milk thistle fruits as a promising raw material of plant origin in
the technology of production of biologically active food additives // Food industry. 2018. No. 9. P. 8-12.
Durnova N.A., Afanasyeva G.A., Kurchatova M.N., Zarayeva N.V., Golikov A.G.,
Bucharskaya A.B., Plastun V.O., Andreeva N.V. The content of oxidative stress markers in
blood plasma under the influence of extracts of common aurantium, sandy everlasting,
anthocyanin form of common corn under conditions of induced oxidative stress - // Exp. and clinical pharmacology 2015, 78, 7, 36-40.
On the issue of standardization of medicinal plant materials in the creation of phyto
preparations. Message 1. Evaluation of immortelle flowers for the content of biologically active compounds / V.P. Georgievskiy [et al.] // Pharmacom. - 2017. - No. 3, - P. 34-57.
Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties / D. Pljevljakusi [et al.] // Frontiers in Plant Science. - 2018. - Vol. 9. - P. 1123-1135.
Khalilova Sh.R., Pulatova D.K., Urmanova F.F. Study of the elemental composition of the above-ground part of red clover // Pharmaceutical journal. - Tashkent, 2012.-№4. - P.26-28.
Khalilova Sh.R. Elemental composition of herbal collection with anti-sclerotic activity // Ecological Bulletin of Uzbekistan. - 2023. - No. 4 (8). - P. 65-69.
Slivkin A.I., Trineeva O.V. Study of the elemental composition of medicinal plant materials by mass spectrometry (using stinging nettle leaves and sea buckthorn fruits as an example) // Bulletin of the Voronezh State University. Series: Chemistry. Biology. Pharmacy. - 2016.- No.1.-P.152-155.